Parkinson's device shows promise in trial

What could be one of the most significant advances in the treatment of Parkinson's disease in the last 50 years has been under testing at 15 medical centers around the country, including the University of Florida and the University of Miami.

According to an article posted last week on the online version of the journal The Lancet Neurology, test subjects with advanced Parkinson's disease who received constant current deep brain stimulation experiences improved motor symptoms and quality of life.
 

UCSD launches major study of Parkinson’s

The first and most common sign of Parkinson’s disease — the second most common neurodegenerative disorder after Alzheimer’s — is trembling of a hand, foot, arm or leg, a shaking that progressively worsens.

Over time, other symptoms can appear: slowed movement, stooped posture, a shuffling gait. Changes in personality, depression, dementia, insomnia and speech impairments may also occur. Each year, more than 50,000 new cases of Parkinson’s are reported in the United States. Roughly 500,000 Americans have the disease, whose cause or causes are not known.
 

Can we cope with the rising tide of Parkinson's disease?

Parkinson’s disease is on the rise. The number of sufferers could reach 162,000 by the end of the decade and campaigners fear that already stretched services will be unable to cope with the soaring numbers.

I have to agree, and it pays to be well informed about the condition should you or an elderly relative develop it.
 

Depomed begins Phase II Parkinson's disease trial

Depomed has commenced a Phase II trial of DM-1992, a gastric-retentive, extended-release formulation of carbidopa/levodopa, in patients with advanced Parkinson's disease with motor fluctuations.

The randomized, active-controlled, open-label trial is designed to enroll at 8 US clinical centers up to 45 patients with Parkinson's disease with motor fluctuations.
 

US Scientists Identify Protein Contributing To Symptoms Of Parkinson's Disease

Scientists at the San Francisco-based Gladstone Institutes, an independent and nonprofit biomedical-research organization, have identified a protein that exacerbates symptoms of Parkinson's disease.

It is a discovery that could one day lead to new treatments for people who suffer from this devastating neurodegenerative illness, China's Xinhua news agency reported.
 

Has your spouse stopped smiling? Parkinson's could be the cause

Parkinson’s, a degenerative brain disease for which there is no known cause or cure, may go undiagnosed and untreated for years.

While the most common symptom is the tremor associated with the disease, there are other signs that may precede the tell-tale trembling—a slowness or stiffness in walking, soreness or aching muscles or joints—usually more on one side than the other—problems with balance, or difficulties with speaking or writing, says Dr. Bill Brown.
 

Path Is Found for the Spread of Alzheimer’s

Alzheimer’s disease seems to spread like an infection from brain cell to brain cell, two new studies in mice have found. But instead of viruses or bacteria, what is being spread is a distorted protein known as tau.
 

New technology helps scientists observe Parkinson's cell development

In the US alone, at least 500,000 people suffer from Parkinson's disease, a neurological disorder that affects a person's ability to control his or her movement. New technology from the University of Bonn in Germany lets researchers observe the development of the brain cells responsible for the disease.
 

Promising Early Results for a Drug to Treat Alzheimer's, Parkinson's

As many as 5.4 million Americans currently suffer from Alzheimer's disease, which is expected to afflict over 16 million by 2050. Recently, however, a new synthetic drug has been developed that may change that number.

The compound, known as J147, has been shown to halt the progressive brain damage associated with Alzheimer's in laboratory animals. It also improves cognitive function in animal models of the disease.
 

Iron accumulation linked to neurodegenerative diseases

Parkinson's and Alzheimer's could be caused by an accumulation of iron in regions of the brain, Australian researchers have found. Following this discovery, the team went on to actually prevent neurodegeneration in transgenic mice by giving them an iron chelator. The finding could offer new avenues of investigation for finding treatments for these incurable diseases.
 

Laser targeting could help fight Parkinson's

Innovative research at San Francisco's Gladstone Institutes could lead to a new treatment for fighting Parkinson's disease. Research using lasers is pointing the way to a new target for drugs.
 

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